A Visit to the Animal Kingdom in Florida Essay Example for Free

A Visit to the Animal Kingdom in Florida Essay English Reflective Essay Florida is portrayed as a fantasy land where Mickey Mouse greets you around every corner and where Cinderella actually lives, where days go by without a single drop of rain and the sky is consistently perfectly blue. However this was the farthest thing from my mind as I sat in an immense carbon-emmiting monster whose air conditioning has spluttered and died and while the heavens poured the air was so thick and mucky that flies were sticking to the windshield as we drove, only to be washed away by the drowning rain. As this was happening, my dad who was yet to figure out his left from his right had the near-miracle task of finding our hotel. Which was almost impossible because visibility was limited to about a yard and that requires great concentration, which was hard to find after the fiasco at the airport. Day 2 To my great excitement, Animal Kingdom was our first theme park, rather disappointing though what was hyped up to be a splendour of animal based excitement turned out to be a zoo with the odd thrill. However my memory of the first day was largely marred by Dad; with his new and shiny American muscle car; forgot that when all four doors were shut the lock system was activated. All hell broke lose! With my mum muttering and rambling nonchalantly and quietly with the odd distinguishable, God.. men and my dad, the man of the household and the decisive being, who was spouting all sorts of obscenities and was spanking the car,lightly so no damage was done but gave the impression that somehow it was the cars fault, it was up to me (seeming the only level headed member of the family) to aqcuire the basic survival needs such as food and water. With out park tickets being used for the day there was no way of buying fresh water. Giving up on the task of survival and surrending to the fate of the great over-powering Florida sunshine that was gobbling up every ounce of liquid, I went to a little ledge at the very far side of the car park and with ironic timing the edge of my eye caught sight of a little pool. And just like an oasis in the middle of the Sahara desert the temptation to drink from this minor miracle was extreme. As I squatted and stared while heavily drooling with my mouth arid there was a conflict of conscience apparent in my head. The good side was reciting the well known fact that one of the locals had stated, In every pool of water in Florida there is an alligator. The other evil side accompanied by my sailva and most major organs, was willing to tempt fate yet my good conscience claimed noble victory and I was left to dessicate. And looking back on it, it was probably a wise decision, however the journey back to the apartment was like a front row seat between Mohammed Ali and Mike Tyson.

Marketing Mix: Tactical Components To Promote Sales

Marketing Mix: Tactical Components To Promote Sales Carlsberg is also one of the largest brewers in Europe. Moreover, Carlsberg is headquartered in Valby in Copenhagen, Denmark. Carlsberg beer portfolio includes more than 500 brands and they are varies significantly in term of volume, price, target audience and geographic penetration. The companys main brand is Carlsberg Beer but it also brews Tuborg as well too. In January 2001, Carlsberg breweries decided to merge with the Norwegian brewery group Orkla ASA and later Carlsberg has become the fifth largest brewery group in the world. Currently, Povl Krogsgaar-Larsen is the Chairman of the Executive Board of Carlsberg Foundation while Jess Soderberg is the Deputy Chairman of the Executive Board of Carlsberg Foundation. Meanwhile, Flemming Besenbacher is one of the members of the Executive Board of Carlsberg Foundation from 2005 until today. 1.1 History Background Carlsberg was constituted in 1847 by J.C. Jacobsen on a hill at Valby. In order to expand the brand name of Carlsberg, it decided to start its exportation in the year 1868. In 1870, Carlsberg had started to become a very successful brewery and the founder, J.C. Jacobsen wanted to share his business with his country. In 1875, the Carlsberg Research Centre was established to research on scientific problem related to brewing and pioneered the very latest brewing technology and techniques. There are more than 1000 scientists devoted to the art of quality beer manufacturing currently. J.C. Jacobson established the Carlsberg Foundation in 1876. In the year 1906, the Old Carlsberg and New Carlsberg have merged and changed the name to Carlsberg breweries due to the division of production was not viable in the long term. As for today, Carlsberg is the beer for modern young people who speak one language in the world with no boundaries. As for information, the Carlsberg brand also provides support to various contests in the world, such as golf tournaments in Asia and English Liverpool Football Club. Carlsberg has it owns organization target, mission and vision. The mission of Carlsberg Company is to be a dynamic provider of quality beers and its also bring its exciting brand, innovative culture and committed teams which will brings people together and add more enjoyment in life. Furthermore, their companys vision is probably the leading the beer company among the world in order to become the first choice of the consumers, customers and employees and also by fully understanding their needs and proactively driving market development. 2.0 What is Marketing Mix? Marketing mix is a combination of tactical components to promote the sales of a product or service (MarketingTeacher, 2010). The firm can control the marketing mix in order to achieve specific goals within a dynamic marketing environment. Basically, the major marketing decision can be divided into four categories which are known as product, price, promotion and place (also known as 4Ps). Product Product is a complex combination of tangible and intangible attributes that provide satisfaction and benefits to the society such as the good, service and idea (Prentice Hall, 2008). When marketing a product, entrepreneurs need to consider and decide the factors which are quality, design, features, variety, utility, branding, packaging and labeling of a particular product. Carlsberg decided to carry out line extensions to extend its brand names to new forms, colors, sizes, ingredients or flavor of its existing product categories (Prentice Hall, 2008). Carlsberg has produced various types of beers in the market throughout the globe and they also try to launch different flavors of beers as they know that individual has different taste and preference for the beer products. By doing this, Carlsberg can be able to satisfy the consumers needs and wants. These are the popular types of beers of Carlsberg: Carlsberg Elephant Carlsberg Lager Tabor Gold Special Brew Tabor Green Danish Royal Stout Ginseng Carlsberg is made from pale lager malt, bittering hops, aroma hops and Carlsberg bottom fermenting yeast. However, Carlsberg has launched different types of beer which can match with various types of dishes, such as seafood, vegetarian, cheese and others (CarlsbergGroup, 2010). Carlsbergs beer products are considered as the convenience goods in consumer product due to the beer products is considered as an inexpensive item which consumers buy frequently and do not do much comparison with other substitute beer products. So, Carlsberg company will differentiate their beer products, produce quality beers, create nice style and design, wrap with unique packaging and labels in order to distinguish itself with its competitors in the global market, such as Heineken and Tiger. Besides, the raw materials that used to produce the beers are the malted barley, hops, yeast, gluten and water. The quality level is different with its competitors in the market because the type of the raw materials that Carlsberg used is not the same. For example, the ways they planted the hops which is one of the raw ingredients are different, so it will end up with different kind of taste. There are also some safety policies in Carlsberg, each of every branch that brews Carlsberg under license, they need to send every type of beers of its sample for once a month for the tasting panel to test in order to ensure the quality of the products (CarlsbergGroup, 2010). So, Carlsberg can consistently deliver the quality that customers pay for. However, one of the Carlsbergs competitors, Heineken, the company produced Buckler which is one of their beer products that is non-alcoholic. So, Heineken can target those young adults and all the religions in the world to buy its non-alcoholic products. Carlsberg did not produce any non-alcohol drink and it might lose its sales because Heineken targets all the consumers irregardless their religion in order to boost up their sale and competed with Carlsberg. Therefore, Carlsberg should also produce non-alcohol drink in order to compete with its tough competitors, Heineken. 3.1 Packaging In the packaging aspect, Carlsberg company uses aluminium cans and glass bottle which can be recycled. The purpose of the packaging is to protect the product from damage and assist retailers in attracting attention to the product (Prentice Hall, 2008). The diagram below shows the difference between the packaging designs of the Carlsberg Lager. BEFORE AFTER Changes of the packaging design of Carlsberg Lager. By doing this, Carlsberg can create instant consumer recognition of the company or brand. Moreover, by making the packaging design unique, Carlsberg can competes with its competitors and its products packaging can also catch the attention of the consumers even if its products are on the same retail store shelves with other substitute beers. For example, Carlsberg started to use environmentally responsible packaging materials and packaging the Carlsberg lager into a unique style glass bottle and less used of papers on it. However, some elderly customers might not be able to see the words that are curved on the Carlsberg Lagers bottle and end up buying other substitute beers that the words can be see clearly. So, Carlsberg should also pay attention on the minority consumers and improve its packaging to look more outstanding than the other beer brands in the market. 3.2 Labeling Labels can be ranged from simple tags attached to products to complex graphics that are part of the package (Prentice Hall, 2008). Moreover, Carlsberg labels its products might also help to promote its products and also support its positioning. As for information, majority of the consumers will look at the percentage of the alcohol of the beer products and they prefer to buy those beer products contain with high percentage of alcohol. Carlsberg labels their beer products in detail: Carlsberg Special Brew It contains 12kcal of calories, 1.1g of carbohydrates, and 2.6g of alcohol. Carlsberg Lager It contains 12kcl of calories, 1.1g of carbohydrates, and 1.1g of alcohol. Tabor It contains 12kcl of calories, 1.1g of carbohydrates, and 1.4g of alcohol. Carlsberg Elephant It contains 13.75kcl of calories, 1.3g of carbohydrates, and 2.9 g of alcohol. Danish Royal Stout Ginseng It contains 15kcl of calories, 1.1g of carbohydrates, and 0.1g of alcohol. Tabor Gold It contains 12kc of calories, 1.1g of carbohydrates, and 2.3g alcohol. Besides that, Carlsberg ensures that their labels contain all the required information and also stated on its products that young adults who are below the age of 18 could not consume its beer products. 3.3 Branding Branding is important to the company because branding can add value to a product. Consumers prefer to buy goods by viewing the brand of the particular goods in the market. Since 1904, Carlsberg has a strong and well-known brand name in the beer industry. The slogan of Carlsberg is Probably the best lager in the world. Previously, Carlsbergs original logos include the swastika and an elephant. However, the world famous Carlsberg logo was introduced by Thorvald Bindesbell in the year 1904, for the launch of Carlsberg pilsner (Logo Design, 2010). The crown on the logo stands for the companys association with the Royal Danish Court. Pricing Price is the amount of money charged for a product or service (Prentice Hall, 2008). It is important to set a price for a product to create and capture customer values in the market. In Malaysia, the government has an authority to set the price for Carlsbergs products which is banned from Muslim. Several country like Vietnam, Sri Lanka and Malaysia have implemented piecemeal legislation such as banning the advertising on TV for any alcoholic beverages but the alcohol companies still have the right and freedom to promote their products. In addition to duties and excise tax, the government levies a sales tax of 20 per cent on the Carlsbergs beer product. As Carlsberg consumption is consider as price-sensitive, major changes in taxes may have an impact on demand. In Russia, an extreme 200% increase in excise duties on beer was implemented in January 2010, and in July 2009 the Ukraine implemented a significant increase of 94% in beer excise duty (Bloomberg, 2010). Carlsberg has carry out thorough scenario planning for 2010 and subsequent years based on already known and anticipated increases in beer excise duty levels. The scenarios include evaluation of prices, packaging and product mix, regional and national market positions and microeconomic factors such as changes in supply and demand for various input costs. Price list of Carlsberg Products The tables above show the price list of the product of both company according to the types of beers and the size volume of the beers. We have converted the price of each product from the United State Dollar ($) to Ringgit Malaysia (RM). 4.1 Internal and external considerations Every country has different pricing for Carlsbergs beer products. For example, Malaysia is an Islamic country. So, malays are not allowed to consume alcoholic drinks. The price of Carlsberg in Malaysia supposedly to be charged in a lower price compared to non-Islamic country. There are some areas in Malaysia which have duty-free for Carlsberg such as Pulau Langkawi. 4.2 Pricing Strategies Price-Adjustment Strategies Segmented pricing: Segmented pricing is to adjust the price to allow for differences in customers, products or locations (Prentice hall, 2008). Carlsberg company uses location pricing, so the price of Carlsberg can be adjusted and flexible but it depends on different country and even in restaurants. Carlsberg focus their sales in pub, restaurants or clubbing place. For instance, comparing the price of Carlsberg between pub and mini market, it seems obviously that the price of Carlsberg in pub would be relatively higher than mini market because people who go to pub are found to be able to afford it and the area of the pub is considered as high class. Carlsberg implements Everyday low pricing (EDLP) which involves charging a constant everyday low price with few or no temporary price discounts. It usually will have some discounts during the festival seasons like Chinese New Year and Christmas. Besides that, Carlsberg use pricing at or near which is one of the pricing strategies. There are few substitute beer products in the market, so the price of the Carlsbergs products will be the same or slightly different with the other substitute beer products. Thus, it can prevent the happening of the price war between Carlsberg and other beer brands. As for information, the price of Carlsbergs products are cheaper compared to the price of Heinekens product but it is slightly lower than the price of Heinekens product. However, the price of Carlsberg and Tiger are the same regardless the size of the beer or packaging. This will be tough for Carlsberg to boost up its sales due to the price for Carlsberg and Tiger are the same in the market. Carlsberg can increase its sales by improving the quality of the beers and give out free gift whenever consumers purchase a carton of Carlbergs beer products. By giving out free gift or limited edition stuff, it will attract the consumers to buy Carlsbergs beer products rather than buying other substitute beer brands in the market. 5.0 Promotion: Carlsberg is well-known in 105 countries such as Japan, Australia, Africa, China, India, and Malaysia, etc and sold in more than 150 markets. Besides that, Carlsberg has adopted some aggressive promotions around the world to pursuit people consume and aware it. In order to compete with its competitors, promotion must be done in order to increase the reputation, generate sales and profits. There are few strong beer brand eager to compete with Carlsberg since Carlsberg is an international business which have branches all around the world, such as Asia, Europe, and other countries. Promotion tactics for Carlsberg are advertising, public relations, sale promotion and personal selling. Moreover, Carlsberg is creating brand awareness in the public. Its public relations is Carlsberg Hue Zing Education Fund (CEF) which give out Studies Loan to all Malaysian citizens who are enrolled in local or foreign institutions of higher learning hold certificate in UEC, SPM or STPM, or any higher certificate. In the Year 2009, the Carlsberg Hue Zing Education Fund had allocated about RM450, 000 which had aided 31 students in need of financial assistance. By doing this, Malaysia citizens will have a good impression on Carlsberg and tend to consume its beer products due to other beer brands never adopt this strategy to create awareness for their products. Carlsberg was crowned the Grand Prize winner of the 11 annual Chinese New Year greeting advertisement award organized by China Press and Nan yang Siang Pau. It cleverly illustrates the transformation of the Chinese character from Ox to Life by adding the iconic Carlsberg swoosh. Furthermore, Carlsberg also have produced their own bottle opener which had their brand name on stated on it. The Glass Beer which label with the logo and Carlsberg Pilsner is also one of the promotion for Carlsberg in Malaysia. 5.1 Advertising Case 1 The contest open to all non-Muslim residents of Malaysia ONLY. Join the Carlsberg Monaco Promotion Contest now and you could win yourself an all expenses paid holiday on private yacht in Monaco. Buy the Carlberg beers that carry a scratch-to-win sticker , scratch it to get the code and submit the code complete with a slogan I am inspired à ¢Ã¢â€š ¬Ã‚ ¦. (in 20 words or less) using SMS or via the website. For more informations, terms and conditions , please visit the contests site. Prizes : Grand Prize: 7D/6N all expenses paid holiday on private yacht in Monaco for 4 person Special Prize: 11 x 3D/2N paid holiday and yacht experience in Langkawi for 2 persons Weekly Prize: 15 x iPOD Shuffle (1GB) Contest End : On 25th May 2007 Posted: April 30, 2007 by ContestStation.net in Buy Win Contests As the case 1 above, we can see that in order to increase their sales, Carlsberg create a campaign, which provide scratch-to-win sticker to some Carlsberg beer and the participants are required to provide a slogan with the requirement, free traveling is available if they win in the competition. Meanwhile, Carlsberg can also get some inspiration of Slogan from customers and knows more about their consumers. This will create a win-win situation which both the consumers and Carlsberg gain benefit too. In this case, Carlsberg shows that they take importance on the political environment on Malaysia. Malaysia is an Islamic country and alcoholic drinks is illegal in the past, after few years, the government allowed alcoholic drinks to be imported into Malaysia but with the condition that Islamic people are not allowed to purchased or consumed alcoholic drinks. So, Carlsberg only opened this competition for non-Muslim which they are allowed to purchase alcoholic drinks. This shows that Carlsberg did a research before they conduct this activity in Malaysia. Assuming if Carlsberg ignore the rule and regulations, the government will take action on them, or even banned them from importing the alcoholic drinks to Malaysia. 5.2 Direct Mail Direct Mail is a method of advertising to increase the awareness of what promotion does the company had. It is now being claimed that is the fastest and the most saving cost in order to advertise. Carlsberg company spends money on buying the database to record the customers information, such as income level, race, age, taste and preference. By doing this, mailing to the right consumers to promote Carlsbergs beer products will be much more effective than mailing to those consumers who are not interested in alcoholic drinks. So, Carlsberg can send promotion via email to the customers to inform them about their new beer products and contest. However, one of the problems being faced by Carlsberg is that their name was being used by illegal organization which used their company address to scam people money. As shown in below, one of the consumers received the email which was send by the scammer and the email stated that she won a lottery which up to 650,000.00 Pounds from Carlsberg Beer Carlsberg Malta Company. When she attempted to called the contact number that was provided in the mail, she was shocked to find out that the people ask her to pay a few thousand pounds for the bank transfer fees before she can get the rewards. Date: Sun, 29 Jun 2008 03:27:09 -0600 (MDT) From: Carlsberg Company Promotion [emailprotected] Reply-To: [emailprotected] Subject: You Won 650.000.00 Pounds Sterlings: File For Clam now Carlsberg UK Ltd, Jacobsen House 140 Bridge Street, Northampton, NN1 1PZ ***PROMOTION NOTIFICATION*** Dear Winner, This is to inform you of the Award of Six Hundred and Fifty Thousand Pounds (650,000.00 Pounds) from Carlsberg Beer Carlsberg Malta Company.This Promotion Award is to raise the profile of Carlsberg Beer Carlsberg Malta Products consumers males / females in rural and urban Areas. The online promotions email lists were generated from the World Wide Web. This promotion takes place annually to challenge and to take market share from the popular Dutch import beer. The tactics included live events, local campaigns and general buzz to establish the brand one neighborhood at a time in major urban / rural Areas.Your Email Ref Number falls within our European booklet representatives office in United Kingdom . In view of this, your Award of Six Hundred and Fifty Thousand Pounds Sterlings (650,000.00 Pounds Sterlings) will be released to you by will commence the process to facilitate the release of your funds as soon as you contact him, find below the contact details Mr. Edward Phil Processing Director. Email: [emailprotected] Tel: +44 70457 24289 He will brief you on steps to be taken for due processing and remittance of your prize money. File in for your Claims by Furnishing your Fiduciary Agent the information below. VERIFICATION AND FUNDS RELEASE FORM 1. FULL NAMES:________________ 2. ADDRESS:_________City_________State________Postcode_______Country_____ 3. SEX:________________ 4. AGE:________________ 5. OCCUPATION:________________ 6. TELEPHONE NUMBER:________________ 7. NATIONALITY:____________________ Mode Of Transfer: (Bank to Bank online Transfer) From the management of Carlsberg Company UK we would like to say a big congratulation to you Sincerely, Mrs. Dianne Thompson Online Coordinator, Carlsberg Beer Malta Breweries In this case, Carlsberg should be aware of scam organization in the world and it should start to take actions to solve the serious scamming problems which will harm the company brand name in the future. Carlsberg can publishes through newspaper or via Email that they would never organize any contest which will need the customers to bank in a certain amount of money in order to win prizes. The promotion mix of Carlsberg is not very efficient because it is lacked of public relation. Therefore, if the consumers give any comments or suggestions, Carlsberg can make any adjustment to fulfill the consumer wants and improve their beer products quality in the future. 6.0 Place: Carlsberg company distributes its products throughtout the world. Carlsberg has divided their market into four groups which are Afica and Middle East, Americas, Asia and Europe. There are about 45,000 people are working for Carlsberg Group. Besides that, Carlsbergs products are available in exactly 314 countries all over the world. Furthermore, Carlsberg also has the same distribution channel with Heineken (its competitor) such as the wholesale distribution and retail distribution to distribute their products to the customers. Carlsberg will deliver their products to a combination of convience store or hypermarkers like Tesco or Jusco. Carlsberg does not have any distrbution center like Heineken or Tiger because Carlsberg focus on the retail distribution to distribute their products. Some of the example of the retail distribution are the pubs, clubs or bars. Carlsberg will establish alliance with some of the retail distribution to increase their sales. The market of Carlsberg in Africa is categorized according to the geographical. They made the segmentation into West Africa, Central Africa, Southern Africa, Eastern Africa and also North Africa. The Carlsberg Group has been active in western Africa for many years. In central Africa, currently there are only four markets present in Central Africa which is Gabon, Congo, Cameroon and Equatorial Guinea. In Cameroon, Les Brasseries du Cameroun has been producing Tuborg Gold locally since 1979, along with the range of local brands. Cameroon is a very competitive market compared to the rest of the region, with the consumption of 25 liters per person per year. In December 1969, Carlsberg Brewery Malaysia Berhad began brewing with Carlsberg Green Label beer locally in 1972. The Carlsberg brand had become the part of daily life and it is now the undisputed market leader with more than a 50% share of the Malaysian beer market. Carlsberg Malaysia has aimed to be at the forefront of innovation and quality and always led the market with dynamic product launches and massive consumer campaigns. In 2008, Carlsberg Green Label received Malaysias Gold Most Trusted Brand Award for the ninth consecutive year in the Readers Digest consumer survey. In the same year, Carlsberg Malaysia was also announced as the winner of the 2008 Strongest Winning Culture Award amongst all the Carlsberg Group Company across the world. Furthermore, Carlsberg company plans to enter into the Germanys market. There are about 1300 breweries in Germany which is quite a lot of number compare to other small retails. The Germany beer is known as Carlsberg Deutschland. The Germany beer market has been rather sheltered from the rest of the world because of the German Reinheitsgebot regulation, which dated back to the year of 1516. In 2004, Carlsberg acquires a majority shareholding in Holsten-Brauerei. The market position of Carlsberg in Northern Germany is second, while at the whole Germany is the fifth. As for the distribution part, we suggest that Carlsberg should follow the steps of Heineken and Tiger (its competitors) to open several distribution center in many countries, so that the consumers can be able to consume Carlsbergs beer products at anytime and anywhere. Besides that, Carlsberg should also built some distribution center at the rural area, although the place was not well developed. By doing this, more and more people will start to know Carlsbergs brand name throughout the world regardless in the city or rural area. Stem Cells: History, Properties and Research Stem Cells: History, Properties and Research History Stem cells  are  cells  found in all multi cellular  organisms. They are characterized by the ability to renew themselves through  mitotic  cell division and  differentiate  into a diverse range of specialized cell types. Research in the stem cell field grew out of findings by  Ernest A. McCulloch  and James E. Till  at the  University of Toronto  in the 1960s The two broad types of mammalian stem cells are:  embryonic stem cells  that are isolated from the  inner cell mass  of  blastocysts, and  adult stem cells  that are found in adult tissues. In a developing  embryo, stem cells can differentiate into all of the specialized embryonic tissues. In adult  organisms, stem cells and  progenitor cells  act as a repair system for the body, replenishing specialized cells, but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues. Stem cells can now be grown and transformed into specialized cells with characteristics consistent with cells of various tissues such as muscles or nerves through  cell culture. Highly plastic adult stem cells from a variety of sources, including  umbilical cord blood  and  bone marrow, are routinely used in medical therapies. Embryonic  cell lines  and  autologous  embryonic stem cells generated through  therapeutic cloning  have also been proposed as promising candidates for future therapies Contents (Jump to) 1  Properties 1.1  Self-renewal 1.2  Potency definitions 1.3  Identification 2  Embryonic 3  Adult 4  Amniotic 5  Induced pluripotent 6  Lineage 7  Treatments 8  Research patents 9  Key research events 10  References Properties The classical definition of a stem cell requires that it possess two properties: Self-renewal   the ability to go through numerous  cycles  of  cell division  while maintaining the undifferentiated state. Potency   the capacity to  differentiate  into specialized cell types. In the strictest sense, this requires stem cells to be either  totipotent  or  pluripotent   to be able to give rise to any mature cell type, although  multipotent  or  unipotent  progenitor cells  are sometimes referred to as stem cells. Self-renewal Two mechanisms exist to ensure that the stem cell population is maintained: Obligatory asymmetric replication   a stem cell divides into one  daughter cell  that is identical to the original stem cell, and another daughter cell that is differentiated Stochastic differentiation   when one stem cell develops into two differentiated daughter cells, another stem cell undergoes  mitosis  and produces two stem cells identical to the original. Potency definitions Pluripotent, embryonic stem cells originate as inner mass cells within a blastocyst. The stem cells can become any tissue in the body, excluding a placenta. Only the morulas cells are totipotent, able to become all tissues and a placenta. Human  embryonic  stem cells A: Cell colonies that are not yet differentiated. B:  Nerve  cell Potency  specifies the differentiation potential (the potential to differentiate into different cell types) of the stem cell. Totipotent  (a.k.a  omnipotent) stem cells can differentiate into embryonic and extraembryonic cell types. Such cells can construct a complete, viable, organism.  These cells are produced from the fusion of an egg and sperm cell. Cells produced by the first few divisions of the fertilized egg are also totipotent. Pluripotent  stem cells are the descendants of totipotent cells and can differentiate into nearly all cells,  i.e. cells derived from any of the three  germ layers. Multipotent  stem cells can differentiate into a number of cells, but only those of a closely related family of cells. Oligopotent  stem cells can differentiate into only a few cells, such as lymphoid or myeloid stem cells. Unipotent  cells can produce only one cell type, their own,  but have the property of self-renewal which distinguishes them from non-stem cells (e.g. muscle stem cells). Identification The practical definition of a stem cell is the functional definition a cell that has the potential to regenerate tissue over a lifetime. For example, the gold standard test for a bone marrow or hematopoietic stem cell (HSC) is the ability to transplant one cell and save an individual without HSCs. In this case, a stem cell must be able to produce new blood cells and immune cells over a long term, demonstrating potency. It should also be possible to isolate stem cells from the transplanted individual, which can themselves be transplanted into another individual without HSCs, demonstrating that the stem cell was able to self-renew. Properties of stem cells can be illustrated  in vitro, using methods such as  clonogenic assays, where single cells are characterized by their ability to differentiate and self-renew.  As well, stem cells can be isolated based on a distinctive set of cell surface markers. However,  in vitro  culture conditions can alter the behavior of cells, making it unclear whether the cells will behave in a similar manner  in vivo. Considerable debate exists whether some proposed adult cell populations are truly stem cells. Embryonic Embryonic stem cell lines  (ES cell lines) are cultures of cells derived from the  epiblast  tissue of the  inner cell mass  (ICM) of a  blastocyst  or earliermorula  stage embryos.  A blastocyst is an early stage  embryo-approximately four to five days old in humans and consisting of 50-150 cells. ES cells are  pluripotent  and give rise during development to all derivatives of the three primary  germ layers: ectoderm, endoderm and mesoderm. In other words, they can develop into each of the more than 200 cell types of the adult  body  when given sufficient and necessary stimulation for a specific cell type. They do not contribute to the extra-embryonic membranes or the  placenta. Nearly all research to date has taken place using mouse embryonic stem cells (mES) or human embryonic stem cells (hES). Both have the essential stem cell characteristics, yet they require very different environments in order to maintain an undifferentiated state. Mouse ES cells are grown on a layer of gelatin and require the presence of Leukemia Inhibitory Factor (LIF). Human ES cells are grown on a feeder layer of mouse embryonic  fibroblasts(MEFs) and require the presence of basic Fibroblast Growth Factor (bFGF or FGF-2).  Without optimal culture conditions or genetic manipulation, embryonic stem cells will rapidly differentiate. A human embryonic stem cell is also defined by the presence of several transcription factors and cell surface proteins. The transcription factors  Oct-4,Nanog, and  Sox2  form the core regulatory network that ensures the suppression of genes that lead to differentiation and the maintenance of pluripotency.  The cell surface antigens most commonly used to identify hES cells are the glycolipids SSEA3 and SSEA4 and the keratan sulfate antigens Tra-1-60 and Tra-1-81. The molecular definition of a stem cell includes many more proteins and continues to be a topic of research. After nearly ten years of research,  there are no approved treatments using embryonic stem cells. The first human trial was approved by the US Food Drug Administration in January 2009.  However, as of August 2010, the first human trial had not yet been initiated. Although, The first human medical trial for embryonic stem cells started in Atlanta on October 13, 2010 for spinal injury victims. ES cells, being pluripotent cells, require specific signals for correct differentiation if injected directly into another body, ES cells will differentiate into many different types of cells, causing a  teratoma. Differentiating ES cells into usable cells while avoiding transplant rejection are just a few of the hurdles that embryonic stem cell researchers still face.  Many nations currently have  moratoria  on either ES cell research or the production of new ES cell lines. Because of their combined abilities of unlimited expansion and pluripotency, embryonic stem cells remain a the oretically potential source for  regenerative medicine  and tissue replacement after injury or disease. Adult Also known as  somatic stem cells and  germline  (giving rise to gametes) stem cells, they can be found in children, as well as adults. Stem cell division and differentiation.  A stem cell; B progenitor cell; C differentiated cell; 1 symmetric stem cell division; 2 asymmetric stem cell division; 3 progenitor division; 4 terminal differentiation Pluripotent adult stem cells are rare and generally small in number but can be found in a number of tissues including umbilical cord blood.  A great deal of adult stem cell research has focused on clarifying their capacity to divide or self-renew indefinitely and their differentiation potential.  In mice, pluripotent stem cells are directly generated from adult fibroblast cultures. Unfortunately, many mice dont live long with stem cell organs. Most adult stem cells are lineage-restricted (multipotent) and are generally referred to by their tissue origin (mesenchymal stem cell, adipose-derived stem cell,endothelial stem cell, etc.). Adult stem cell treatments have been successfully used for many years to treat leukemia and related bone/blood cancers through bone marrow transplants.  Adult stem cells are also used in veterinary medicine to treat tendon and ligament injuries in horses. The use of adult stem cells in research and therapy is not as  controversial  as  embryonic stem cells, because the production of adult stem cells does not require the destruction of an  embryo. Additionally, because in some instances adult stem cells can be obtained from the intended recipient, (an  autograft) the risk of rejection is essentially non-existent in these situations. Consequently, more US government funding is being provided for adult stem cell research. An extremely rich source for adult mesenchymal stem cells is the developing tooth bud of the mandibular third molar. While considered multipotent they may prove to be pluripotent. The stem cells eventually form enamel (ectodrm), dentin,periodontal ligament, blood vessels, dental pulp, nervous tissues, including a minimum of 29 different unique end organs. Because of extreme ease in collection at 8-10 years of age before calcification and minimal to no morbidity will probably constitute a major source for personal banking, research and multiple therapies. These stem cells have been shown capable of producing hepatocytes. Amniotic Multipotent stem cells are also found in  amniotic fluid. These stem cells are very active, expand extensively without feeders and are not tumorigenic.  Amniotic stem cells  are multipotent and can differentiate in cells of adipogenic, osteogenic, myogenic, endothelial, hepatic and also neuronal lines.  All over the world, universities and research institutes are studying  amniotic fluid  to discover all the qualities of amniotic stem cells, and scientists such as  Anthony Atala  and  Giuseppe Simoni  have discovered important results. From an ethical point of view, stem cells from  amniotic fluid  can solve a lot of problems, because its possible to catch amniotic stem cells without destroying embryos. For example, the Vatican newspaper Osservatore Romano called amniotic stem cell the future of medicine. Its possible to collect amniotic stem cells for donors or for autologuous use: the first US amniotic stem cells bank   opened in Medford, MA, by  Biocell Center  Corporation  Ã‚  and collaborates with various hospitals and universities all over the world Induced pluripotent These are not adult stem cells, but rather reprogrammed cells (e.g. epithelial cells) given pluripotent capabilities. Using genetic reprogramming with protein  transcription factors, pluripotent stem cells equivalent to  embryonic stem cells  have been derived from human adult skin tissue.  Shinya Yamanaka  and his colleagues at  Kyoto University  used the transcription factors Oct3/4, Sox2, c-Myc, and Klf4  in their experiments on cells from human faces.  Junying Yu,  James Thomson, and their colleagues at the  University of Wisconsin-Madison  used a different set of factors, Oct4, Sox2, Nanog and Lin28,  and carried out their experiments using cells from human  foreskin. As a result of the success of these experiments,  Ian Wilmut, who helped create the first cloned animal  Dolly the Sheep, has announced that he will abandon  nuclear transfer  as an avenue of research. Frozen blood samples can be used as a source of induced pluripotent stem cells, opening a new avenue for obtaining the valued cells. Lineage They ensure self-renewal, stem cells undergo two types of cell division (see  Stem cell division and differentiation  diagram). Symmetric division gives rise to two identical daughter cells both endowed with stem cell properties. Asymmetric division, on the other hand, produces only one stem cell and a  progenitor cell  with limited self-renewal potential. Progenitors can go through several rounds of cell division before terminally  differentiating  into a mature cell. It is possible that the molecular distinction between symmetric and asymmetric divisions lies in differential segregation of cell membrane proteins (such as  receptors) between the daughter cells. An alternative theory is that stem cells remain undifferentiated due to environmental cues in their particular niche. Stem cells differentiate when they leave that niche or no longer receive those signals. Studies in  Drosophila  germarium have identified the signals dpp and adherens junctions that prevent germarium stem cells from differentiating. Main article:  Induced Pluripotent Stem Cell The signals that lead to reprogramming of cells to an embryonic-like state are also being investigated. These signal pathways include several  transcription factors  including the  oncogene  c-Myc. Initial studies indicate that transformation of mice cells with a combination of these anti-differentiation signals can reverse differentiation and may allow adult cells to become pluripotent. However, the need to transform these cells with an oncogene may prevent the use of this approach in therapy. Challenging the terminal nature of cellular differentiation and the integrity of lineage commitment, it was recently determined that the somatic expression of combined  transcription factors  can directly induce other defined somatic cell fates; researchers identified three neural-lineage-specific transcription factors that could directly convert mouse  fibroblasts  (skin cells) into fully-functional  neurons. This induced neurons (iN) cell research inspires the researchers to induce other cell types implies that  all  cells are  totipotent: with the proper tools, all cells may form all kinds of tissue. Treatments Medical researchers believe that stem cell therapy has the potential to dramatically change the treatment of human disease. A number of adult stem cell therapies already exist, particularly  bone marrow transplants  that are used to treat  leukemia.  In the future, medical researchers anticipate being able to use technologies derived from stem cell research to treat a wider variety of diseases including  cancer, Parkinsons disease,  spinal cord injuries,  Amyotrophic lateral sclerosis,  multiple sclerosis, and  muscle  damage, amongst a number of other impairments and conditions.  However, there still exists a great deal of social and scientific uncertainty surrounding stem cell research, which could possibly be overcome through public debate and future research, and further education of the public. One concern of treatment is the possible risk that transplanted stem cells could form tumors and have the possibility of becoming cancerous if cell division continues uncontrollably. Stem cells, however, are already studied extensively. While some scientists are hesitant to associate the therapeutic potential of stem cells as the first goal of the research, they find the investigation of stem cells as a goal worthy in itself. Contrarily, supporters of embryonic stem cell research argue that such research should be pursued because the resultant treatments could have significant medical potential. It is also noted that excess embryos created for  in vitro fertilization  could be donated with consent and used for the research Diseases and conditions where stem cell treatment is promising or emerging.  Bone marrow transplantation is, as of 2009, the only established use of stem cells. Research patents The  patents  covering a lot of work on human embryonic stem cells are owned by the  Wisconsin Alumni Research Foundation  (WARF). WARF does not charge academics to study human stem cells but does charge commercial users. WARF sold  Geron Corp.  exclusive rights to work on human stem cells but later sued Geron Corp. to recover some of the previously sold rights. The two sides agreed that Geron Corp. would keep the rights to only three cell types. In 2001, WARF came under public pressure to widen access to human stem-cell technology. These patents are now in doubt as a request for reviewing the  US Patent and Trademark Office  has been filed by non-profit patent-watchdogs  The Foundation for Taxpayer Consumer Rights, and the  Public Patent Foundation  as well as molecular biologist Jeanne Loring of the Burnham Institute. According to them, two of the patents granted to WARF are invalid because they cover a technique published in 1993 for which a patent had already been granted to an Australian researcher. Another part of the challenge states that these techniques, developed by  James A. Thomson, are rendered obvious by a 1990 paper and two textbooks. The outcome of this legal challenge is particularly relevant to the Geron Corp. as it can only license patents that are upheld. Key research events January 2008   Robert Lanza and colleagues at Advanced Cell Technology and UCSF create the first human embryonic stem cells without destruction of the embryo January 2008   Development of human cloned blastocysts following  somatic cell nuclear transfer  with adult fibroblasts. February 2008   Generation of pluripotent stem cells from adult mouse liver and stomach: these iPS cells seem to be more similar to embryonic stem cells than the previously developed iPS cells and not tumorigenic, moreover genes that are required for iPS cells do not need to be inserted into specific sites, which encourages the development of non-viral reprogramming techniques. March 2008 The first published study of successful cartilage regeneration in the human knee using autologous adult mesenchymal stem cells is published by clinicians from Regenerative Sciences. October 2008   Sabine Conrad and colleagues at Tà ¼bingen, Germany generate  pluripotent stem cells  from spermatogonial cells of adult human testis by culturing the cells in vitro under  leukemia inhibitory factor  (LIF) supplementation. 30 October 2008   Embryonic-like stem cells from a single human hair. 1 March 2009   Andras Nagy, Keisuke Kaji,  et al.  discover a way to produce embryonic-like stem cells from normal adult cells by using a novel wrapping procedure to deliver specific genes to adult cells to reprogram them into stem cells without the risks of using a virus to make the change. The use of  electroporation  is said to allow for the temporary insertion of genes into the cell. 28 May 2009  Kim  et al.  announced that they had devised a way to manipulate skin cells to create patient specific induced pluripotent stem cells (iPS), claiming it to be the ultimate stem cell solution. 11 October 2010  First trial of embryonic stem cells in humans References Becker AJ, McCulloch EA, Till JE (1963). Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells.   Siminovitch L, McCulloch EA, Till JE (1963). The distribution of colony-forming cells among spleen colonies.  Journal of Cellular and Comparative Physiology. Tuch BE (2006). Stem cells-a clinical update.  Australian Family Physician. Hans R. Schà ¶ler (2007). The Potential of Stem Cells: An Inventory. In Nikolaus Knoepffler, Dagmar Schipanski, and Stefan Lorenz Sorgner.  Humanbiotechnology as Social Challenge. Ashgate Publishing, Ltd. Mitalipov S, Wolf D (2009).  HYPERLINK http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrezartid=2752493Totipotency, pluripotency and nuclear reprogrammingHYPERLINK http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrezartid=2752493.  Adv Biochem Eng Biotechnol   Ulloa-Montoya F, Verfaillie CM, Hu WS (Jul 2005). Culture systems for pluripotent stem cells.  J Biosci Bioeng.   Friedenstein AJ, Deriglasova UF, Kulagina NN, Panasuk AF, Rudakowa SF, Luria EA, Ruadkow IA (1974). Precursors for fibroblasts in different populations of hematopoietic cells as detected by the  in vitro  colony assay method.  

Chicago Hope :: essays research papers

Chicago Hope, David E. Kelly’s infamous doctor-drama, premiered on September 18, 1994. Six years later, the show was canceled after its final season’s finale, which aired on May 4, 2000. Even though â€Å"Hope† couldn’t beat its direct competitor ER in the ratings race, the show still had a lot of good things going for it. Chicago Hope was nominated for a myriad of highly prestigious awards during its run. Many of these awards were lost to ER and other dramas but leading-lady Christina Lahti did receive both an Emmy and a Golden Globe for her performances on the show. Critic Mark Harris, even when as far as saying, â€Å"Lahti is, no question, the best dramatic actress in prime time.† (Entertainment Weekly, Oct. 4, 1996 p.51) Also, Hector Elizondo received an Emmy for his supporting role and people involved in off screen production won multiple awards. Chicago Hope was loved by critics even when being directly compared to ER. Chicago Hope was basically CBS’s answer to ER; a drama about doctors, taking place in a teaching hospital in Chicago, that aired on Thursdays at ten. The cast was constantly changing due to the constant ratings battle CBS was waging against NBC. Behind the scenes, CBS put its money on Executive Producer/Writer David E. Kelly who, at the time, was just coming off a successful run with Picket Fences; while NBC also went with a big name Producer/Writer/Novelist in Michael Crichton. Also, â€Å"Hope† used numerous directors and guest directors over the course of its six-year run, keeping the show fresh. Aside from the battle with ER and the constantly changing staff, this show definitely met or exceeded all of the requirements for a â€Å"quality TV† series outlined by Professor Robert J. Thompson in his book Television’s Second Golden Age. Chicago Hope was not your everyday TV escape. It was a show that made the viewer actually think about what was going on in both the show and the real world. It brought up issues that actually affected the lives of the people watching. It dealt with controversial issues like death, birth control, and AIDS. In the words of critic Ken Tucker, â€Å"†¦in a fall season with little quality [this is a] solid drama.† (Entertainment Weekly, Sept. 23, 1994 p. 52) Furthermore, â€Å"Hope† was the brainchild of Producer David E. Kelly, which, before the premiere even aired, meant that it was of high quality.

Hawaiian Navigation Essay example -- Ancient History

Hawaiian Navigation How did the Polynesians find their way to Hawaii, over two thousand miles from any other land? Was it over population at home, or political turmoil? Whatever reason for leaving these people used amazing knowledge and skill of the ocean and of the sky to navigate them to this new land. They faced the unknown and braved into the wide-open ocean for long periods of time. The real focus in this paper is on the navigation techniques that they used in these voyages throughout the Pacific. It's impossible to teach someone the significance or the act of loving the stars and the ocean but that's what makes navigation without instruments (wayfinding) so beautiful. One can "give the heavens a meaning his own meaning" says Nainoa Thompson. Anyone can learn the aspects of navigation through personal observation and the study of charts and maps. Thus creative thinking and logic are two important skills in learning the ancient art of wayfinding. It is inspiring to think of how much water the Polynesians covered in the Pacific, over one million square miles, in a time frame of about 1000 years. Some members of the modern Hawaiian community were so impressed that they established the Polynesian Voyaging Society in 1973. They did some voyages throughout the Pacific without the help of instruments for scientific research and education. The topic was so interesting to so many people throughout the South Pacific that the voyages became more about recovering culture and about teaching the art of wayfinding so that it is not lost in time. Revival of Interest: A serious rebirth in Polynesian culture and traditions arouse after the voyages by the Hokule'a. In 1975 a replica of a Polynesian voyaging can... ... circumference. As long as people care about what's going on in the Polynesian revival of culture there will be growth. There will be energy left for people to search out the answers to our questions and the lost secrets of these amazing people who found these islands over 1,500 years ago. References: Baybayan, Chad, Kawaharada, Dennis. ( May 1996 ). Polynesian Voyaging Society Manuel. Honolulu, Hawaii: Polynesian Voyaging Society. Finney, Ben. (1994) Voyage Of Rediscovery. University of California Press. Kyselka, Will. (1987) An Ocean In Mind. Honolulu, Hawaii. University of Hawaii Press. http://leahi.kcc.hawaii.edu/org/pvs/buildloa/html http://leahi.kcc.hawaii.edu/org/pvs/ohanabackground.html

Review of Hunger Games Movie Essay

I thought that The Hunger Games movie was overall an â€Å"ok† film with just the right amount of special affects and action sequences to complement a decent story. The director and producers stuck very close to the book as far as the story goes. This explains why the movie runs for over two hours. Although the events were very accurate, there were certain things that were not explained properly in the movie whichmovie, which changed its interpretation. One thing that bothered me was lack of explanation behind Katniss’s and Peeta’s relationship. I was fortunate enough have analyzed the book so I, or course, knew that the relationship started off as fake in the beginning and kindled into actuality. As a person watching the movie, you would think that Katniss simply fell in love with Peeta as time passed. Within the movie, tThey also neglected to elaborate on the dog-creatures at the end of the story, which were genetically engineered from the dead tributes. The lack of this detail prevented the audience from fully understanding the depravity of the Capital and their general disregard for the people of the districts. Also, Rue’s death was made to look like it was not the fault of Katniss, but another tribute. Again, I think this hurt the movie because it did not depict the type of sacrifices struggles one had to make endure in order to survive the Hunger Games. While the movie lacked some details, others were added in their place to perhaps aid in telling the story the way it was meant to be told. One thing that was added was the behind the scenes meeting between the Game Keeper and the leader of the Capital. These meeting help to reveal the Capital’s hidden agenda with the Hunger Games, which otherwise would be unknown to a person watching the movie without having read the book. Also, they showed the districts rioting at the death of Rue. This is helps to illustrate the hatred and anger that the people of the districts have for the games and I suppose its easier to make that scene than it is to imply it through the houghts of Katniss and dialogue between the characters, like in the book. All in all, I think the movie stuck very close to the book and I found that to be very refreshing. Compared to most movie adaptations, such as the Harry Potter series, its sticks more closely to the story. In the Harry Potter movies, the studio took a fair amount of artistic license with the stories and changed many finite details. This was likely done because of lack of funding and screen time. The Hunger Games did not have this problem probably because the story if more realistic than that of the magic conjuring, broomstick flying Harry Potter. There is little need for computer generated imagery (CGI) in this movie and the book is kept at a reasonable length so the movie did not have to compromise too much. This to me is the thing that it did best and I look forward to seeing the next one.

Physiology Essay

Muscles are responsible for all conscious and unconscious movement. It is how we move and react to an environment. There are three types of muscles in the body include the skeletal muscle, smooth muscle, and the cardiac muscle. Whether you are running, walking, breathing, eating, sleeping, or typing it all involves some sort of muscle action. Muscle cells that shape, form, and outline the whole human skeleton is called a muscle fibers. There are two types of muscle fibers: Type I (slow-twitching fibers) and Type II ( fast-twitching fibers).â€Å"The slow muscles are more efficient at using oxygen to generate more fuel (known as ATP) for continuous, extended muscle contractions over a long time. They fire more slowly than fast twitch fibers and can go for a long time before they fatigue. † (Quiin, 2013) The slow-twitching fibers utilizes an oxidation energy system, or ability to require more oxygen in creating fuel for the muscles, that allows long distance runners to finish a marathon as long as they can. In contrast, Type I muscle fiber is built more for endurance.â€Å"Fast twitch fibers use anaerobic metabolism to create fuel, they are much better at generating short bursts of strength or speed than slow muscles. However, they fatigue more quickly. Fast twitch fibers generally produce the same amount of force per contraction as slow muscles, but they get their name because they are able to fire more rapidly. † (Quiin, 2013) Fast-twitching muscles generate energy from the anaerobic energy system, allowing ‘explosive’ movements for short amount of time before fatigue.Conclusively, Type II fibers are more for a sprinter or agility movements in periods of two or three minutes. To break it down more, there are two types of Type II muscle fibers: Type IIa and Type IIb. Type IIa have both characteristics Type I and Type II fiber that consume both anaerobic and aerobic energy systems. And type IIb is more like fast-twitching fibers with it s anaerobic energy requirements. When it comes to training certain muscles fiber types, everybody is more differently built with one muscle fiber than the other.Some are more of a 300-meter sprinter; others are able to run endlessly. Training for a marathon requires a lot of long distance running; training for a 400 meter shuttle sprint will require more short distance runs. No matter what the case is, the only way to improve performance is to keep working on that area; in return builds endurance for that muscle group. In relation to the previous paragraph, muscles require energy to perform. Depending on the muscle fiber type determines which energy system is used.Adenosine triphosphate, or ATP, is energy that make muscle contraction possible. The energy systems consist of the ATP-PCr system, glycolysis system, and the oxidative system. The ATP-PCr system utilizes stored ATP for quick, ‘explosive’ movements such as releasing a powerful swing with a baseball bat. The gly colysis system â€Å"provides energy for activities of slightly longer duration and lower intensity like strength training. † (Hefferman, 2012) And the oxidative system is used for physical activities that perform for a longer period of time, requiring more oxygen.The first two energy systems are anaerobic, while the third one is aerobic. What all of these systems have in common is they must consume glucose. Glucose is a form of fuel that comes from the foods we eat. Glucose store in the muscles and liver is called glycogen. When the body and muscles need energy, the glycogen goes through glycolysis; in which is broken down to, once again, glucose. Performing an exercise requires the fuel for the contracting muscles. How does the muscle contract? Reason to contract muscle can be with and without conscious.On a segment or bundle of muscles are controlled by a neuron in the nervous system. The neuron is made up a cell body (soma), axon, and dendrites. The neuron is referred to as an excitable tissue that transmits signals into nerve impulses. â€Å"A nerve impulse is an electrical signal that travels along an axon. There is an electrical difference between the inside of the axon and its surroundings, like a tiny battery. When the nerve is activated, there is a sudden change in the voltage across the wall of the axon, caused by the movement of ions in and out of the neuron.† (What are nerve impulses)From contracting muscles to maintaining normal cellular functions, the body requires fuel for energy. Fuel, or calories, is what our body does to metabolize energy. To obtain this fuel, we consume food. Foods we eat made up nutrients and fuel substrates consisting of fat, protein, carbohydrates. Carbohydrates, when broken down, create glucose that is for energy or stored, turns into glycogen, when not in immediate use. Fat is broken down to triglycerides to be used for metabolic energy, and stored as fat when not in immediate use.Protein breaks down into a form of amino acids when used for energy. Carbohydrates and fat are mainly used for all metabolic needs to generate ATP; protein, in a form of amino acids, goes through lipogenesis for cellular energy needs. In event where all fat and carbohydrates are depleted, protein is a last resort for ATP. If you ever noticed on a nutrition label printed on a bag or box of food, sometimes you can see the amount of calories per gram that each substrate has.Carbohydrates and protein stores about four calories per gram, whereas fat contains nine calories per gram; this is one advantage of consuming fat than carbohydrates. Another advantage is fat (triglycerides) can be stored as fat, while carbohydrates require water to form into glycogen for store; this results into water retention (water weight). Disadvantage of fat would be converting into energy (glucose), whereas carbohydrates (glucose) are already broken down and ready to be utilized. This is a reason why marathon runners ‘carb loa d’ days prior the event.Injunction to the first paragraph, the heart is made up of the cardiac muscle. One of the most essential parts of the cardiovascular system, the heart pumps the blood throughout the body transporting oxygen and nutrients to cells. The heart is a very complex organ that consists of â€Å"four cavities, or open spaces, inside the heart that fill with blood. Two of these cavities are called atria. The other two are called ventricles. The two atria form the curved top of the heart. The ventricles meet at the bottom of the heart to form a pointed base which points toward the left side of your chest.The left ventricle contracts most forcefully, so you can best feel your heart pumping on the left side of your chest. † (Unysis) So, the heart pushes the red, oxygen-rich blood from the lungs through the left side of the heart to the rest of the body. As the blood pumps, it delivers the oxygen and flows back to the heart and through the lungs to drop off c arbon dioxide and pick up oxygen. To prevent back flow, heart’s internal structures comprises of valves that open and close with every pump of blood. Another essential part of the cardiovascular is blood.Blood is a fluid containing red blood cells, plasma, antibodies, hormones, enzymes, and nutrients. The purpose of blood consist of transporting oxygen to cells of the body, carry out waste such as carbon dioxide, maintain normal body temperature, and regulate pH levels and hormones. Blood travels through series of vessels. These include arteries (rich-oxygen blood leaving the heart to cells), veins (poor-oxygen blood leaving from the cells through the heart and to the lungs), and capillaries (blood vessel that connects between the veins and arteries). Blood is the life source to sustain life and maintain cellular functions.

Gender Segregation in the Swedish Labour Market Essay

Introduction Sweden and the other Scandinavian countries are widely known for their strong commitment to equality between men and women. During the development of the welfare state the government supported women’s participation in the labor market. This resulted in a high rate of female employment in Sweden today. Regarding this, it is striking that the Swedish labor market has one of the highest degrees of gender segregation in the world and considerable gender inequalities. The roots for this segregation can be seen in the growing welfare state with women starting to work overall in the public and service sector in areas like health care and child-care while men still dominated in the private sector. Policies for women’s integration and several other government measures to desegregate the labor market were implemented and performed in the last years. However, today the gender segregation in Sweden is still at a higher level than in the majority of the other countries in Europe. Th is paper offers an analysis of the Swedish labor market regarding gender with an economical perspective. Occupational Gender Segregation Gender Segregation is one of the most discussed topics in Europe especially in Sweden. The segregation that will be analyzed in this paper can be seen as a result of multidimensional process which is manifested in differences in gender patterns of representation within occupations as well as within different employment contract groups and employment status (http://www.fep.up.pt/investigacao/cete/papers/dp0302.pdf , p. 2). â€Å"Gender segregation means that women and men to a certain extent work in different occupations or in different sectors or under different contractual terms and conditions† (ibid p. 2). The gender-based occupational segregation is both the â€Å"tendency for men and women to be employed in different occupations†, which is the horizontal segregation and the tendency to be employed in â€Å"different positions within the same occupation or occupational group†, the vertical segregation (http://ilo-mirror.library.cornell.edu/public/english/suppo rt/publ/pdf/women.pdf#page=198, p. 191). To measure segregation, the Index of Dissimilarity (ID) is most widely used in the research literature and also in this paper. Its value ranges from 0, which is â€Å"no segregation with equal percent of women and men in each and every occupation† to 1, which is â€Å"complete segregation with female workers in occupations where there are no male workers† (idib., p. 196). It is important to include a discussion of division of work in the households when looking at gender segregation. In Scandinavian countries a two-bread-winner model is the norm with subcontracted work in the households. At the same time, the former typical women’s household work like caring for children, elderly and disabled people was and is more and more taken over by the public sector. This expanding public sector leads to new employments for women and has an impact on the gender segregation which is also worth to be examined (http://www.fep.up.pt/investigacao/cete/papers/dp0302.pdf , p. 2). Facts and figures Sweden has one of the highest female employment rates and a high female education level. At the same time, data indicate that Sweden’s gender segregation is decreasing in the labour market, but still at a high level (http://www.fep.up.pt/investigacao/cete/papers/dp0302.pdf, p. 4). While the gender segregation for the European Union as a whole is still relatively high, the Mediterranean and eastern countries have a rather low segregation in comparison to the high-segregated Nordic countries (http://ec.europa.eu/social/BlobServlet?docId=4028&langId=en, p. 7). A closer look on the Swedish labour market reveals that, especially in the private sector, women are under-presented in jobs at a higher level and they usually have lower positions. Instead a great number of females is employed in the public sector and working part time. Moreover, women still perform two third of all their unpaid work at home (Gender equality and occupational segregation in Nordic labour markets, p. 190). In 1992 one half of all employed female employment worked in the public sector. Whereas, men employment was represented with one-quarter. In general, the labour force participation of women in Sweden is quiet strong. Already in 1990, female participation was at a level of 49,5% in comparison to lower levels in North America (45%) and to other European Countries (39% Gender equality and occupational segregation in Nordic labour markets, p. 194f.). Research proves that Sweden has a relatively high level of occupational segregation by sex. Although the ID decreased from 0,731 in 1970 to 0,641 in 1990, it is still higher than in other countries. The U.S.A. had an ID of 0,55 in 1990 and France 0,60. Furthermore the average of 14 non-Nordic OECD countries was 0,55 (idib, p. 197ff.) A later study of 15 EU members in 2000 shows the same tendency. It ranked Sweden on the second place after Finland according to the ID segregation index (http://www.fep.up.pt/investigacao/cete/papers/dp0302.pdf, p. 32) Further research indicates a proportion of females in female-dominated occupations, which is relatively and absolutely high in comparison to the rest of the European countries except for Norway and Finland, which show a similar labour market structure as Sweden. While the percentage of female employments in occupations with more than 70% females decreased slightly from 72,9% to 69,2% from 1970 to 1970, the proportion of females employed in occupations with more than 90% female dominance even increased in these years from 37,5% to 42,2%. This female dominance is not typical for the rest of Europe. In 1990 the other 14 OECD countries had a percentage of 22% in the occupations with more than 80% females. This is significantly lower than the 58,2% in Sweden (idib, p. 199ff.) The examination of male employment in male-dominant occupations shows similar numbers. This result is, however, not atypical as Sweden is accompanied by the other OECD countries concerning this male dominance (idib, p. 202f.). More recent findings indicate that the female dominance in the public sector is still high. In 2000 the proportion of women’s employment in Sweden’s public sector was 62,1% in comparison to the EU average of 42,7% (http://www.fep.up.pt/investigacao/cete/papers/dp0302.pdf, p. 28) â€Å"Female† and â€Å"male† occupations Due to the gender segregation some jobs are female dominated and others are known as typically male. The table shows the 10 most â€Å"feminized† occupations in Sweden (idib, p. 204). The occupations are associated with either caring, manual dexterity or are related to the typical household-work. On the first place rank â€Å"Dental assistants and other health workers†; in the second place come â€Å"Telephone switch board operators, etc.† and third are â€Å"House keeper in private service, childcare in families and at home†. Still male dominant are technical occupations like chemists and physicists in comparison to female laboratory assistants. Furthermore, typically female occupations can be found in the nursing and teaching area. However, the number of females in teaching decrease according to the rising level of teaching: 96% of pre-primary teachers are women in Nordic countries, but only 30% are female university teachers. Moreover, in the Nordic countries the same as in industrialized countries in general, women are over-represented in the service area (idib., p. 206ff). Vertical Segregation and wage inequalities Women in Sweden are concentrated in lower-paid and lower-status occupations. For instance only 40% of the shop managers are female, whereas 75% of the shop personnel are women (idib., p. 209). Furthermore, in 2000 women in higher level jobs as share of all women in employment was only 20,8% (http://www.fep.up.pt/investigacao/cete/papers/dp0302.pdf, p. 27). Gender gap in earnings can be seen as a consequence of segregation. However, in Sweden the gap is lower than in other countries. While Sweden created many occupations in the public sector, the wage differences were compressed due to a huge influence of union federations and employer associations. Also laws have been established to secure equal pay for equal work. For this reason, the women forced into particular jobs do not earn much lower wages than men and the high level of gender segregation goes along with a relatively low wage gap (http://books.google.de/books?id=-7umiJpO_zIC&pg=PA47&lpg=PA47&dq=gender+segregation,+sweden&source=bl&ots=WME1izrf2g&sig=qxVvzUAEWzaeMrf4qVXbQatotHQ&hl=de&ei=9KL7TKP4HM_sOcaEndUK&sa=X&oi=book_result&ct=result&resnum=7&ved=0CGAQ6AEwBg#v=onepage&q=gender%20segregation%2C%20sweden&f=false, p. 20f.). In fact the gap between earnings is significantly smaller in comparison to other countries. In general women’s wages are relatively high, but still lower than men’s. This is also due to many women working in the public sector where the wages are lower than in the private sector. Another analysis by the European Comission in 2002 shows the women’s wages as a percentage of men’s. In typical male occupations like engine man, skilled or garden worker women earn only 95% to 98% of men’s wage. However, inequalities also exist the other way round. In typical female occupations like nurses or child minder men earn less than women. Women earn up to 105% of men’s wage. It can be stated that differences and inequalities exist, but concerning the wages they are not significant (http://ec.europa.eu/social/BlobServlet?docId=4028&langId=en, p. 80). Impact of increasing female employment on gender segregation The development of the last centuries in the European Union (15 members) does not show a trade-off between increasing segregation and increasing female employment. However, with focus on the short and medium run or with cross country comparison the opposite was found: In particular in the 1990s, there is evidence of a positive correlation between high female employment rates and gender segregation in the labour market on a more or less temporary basis. These study results were also due to the nordic countries including Sweden with their high degree of segregation and high-employment. One reason for this is the common Swedish family which has two breadwinners. With both parents working it is usually the woman who has to work in a â€Å"family friendly occupation† with flexible schedules. For this reason, the positive effect of rising women’s employment in order to drive desegregation may only exist in the long term. (,http://www.fep.up.pt/investigacao/cete/papers/dp0302.pdf p. 3, http://ec.europa.eu/social/BlobServlet?docId=4028&langId=en, p. 35ff.). Government measures Concluding remarks and preview Segregation is not only harmful and discriminating for the people affected by it, but it is also undesirable in high developed and progressive societies. Also the efficiency of the labor market as a whole can be affected negatively. It is highly reasonable that Sweden and the EU take measures to improve equality in the labor market. However, segregation also has a positive side. Some argue that it protects women’s employment from male competition and upholds demand for female labor. The public sector also offer more secure employment especially between 1992 and 1994. This advantage for women is now diminished due to reorganization of the public sector. (Gender equality and occupational segregation in Nordic labour markets Von Helinà ¤ Melkas,Richard Anker,International Labour Office, p. 191).